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Tsan-Wen Lu Selected Research

Fibrolamellar hepatocellular carcinoma

12/2020Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
1/2019Structures of the PKA RIα Holoenzyme with the FLHCC Driver J-PKAcα or Wild-Type PKAcα.

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Tsan-Wen Lu Research Topics

Disease

2Fibrolamellar hepatocellular carcinoma
12/2020 - 01/2019
1Parkinson Disease (Parkinson's Disease)
01/2020
1Liver Neoplasms (Liver Cancer)
01/2020

Drug/Important Bio-Agent (IBA)

2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
12/2020 - 01/2019
2Phosphotransferases (Kinase)IBA
01/2020 - 01/2019
1Proteins (Proteins, Gene)FDA Link
12/2020
1Heat-Shock Proteins (Heat-Shock Protein)IBA
12/2020
1HoloenzymesIBA
12/2020
1Protein Subunits (Protein Subunit)IBA
12/2020
1Oncogene Proteins (Oncogene Protein)IBA
01/2020
1Leucine (L-Leucine)FDA Link
01/2020